Ferrimagnetic Heusler tunnel junctions with fast spin-transfer torque switching enabled by low magnetization.

Magnetic random-access memory that uses magnetic tunnel junction memory cells is a high-performance, non-volatile memory technology that goes beyond traditional charge-based memories. Today, its speed is limited by the high magnetization of the memory storage layer. Here we prepare magnetic tunnel junction memory devices with a low magnetization ferrimagnetic Heusler alloy MnGe as the memory storage layer on technologically relevant amorphous substrates using a combination of a nitride seed layer and a chemical templating layer.

Occurrence and ecological risks of antibiotics and antiparasitics in surface water in urban lakes in Hanoi city, Vietnam.

The presence of antibiotics in the environment is of significant concern due to their adverse effects on aquatic ecosystems. This study provides an assessment of potential ecological risks (RQ) associated with the concentrations of eight antibiotics and antiparasitics (amoxicillin-AMO, azithromycin-AZI, ciprofloxacine-CIP, ofloxacine-OFL, oxfendazole-OXF, lincomycin-LIN, sulfacetamide-SCE and sulfamethoxazole-SME) in the surface water of 13 urban lakes in Hanoi city, Vietnam during the period 2021-2023. The findings revealed considerable variations in the total concentrations of these 8 substances (T), ranging from below the method detection limit (< MDL) to 2240 ng L with an average of 330.

In-depth mass-spectrometry reveals phospho-RAB12 as a blood biomarker of G2019S LRRK2-driven Parkinson's disease.

Leucine-rich repeat kinase 2 (LRRK2) inhibition is a promising disease-modifying therapy for LRRK2-associated Parkinson's disease (L2PD) and idiopathic PD (iPD). However, pharmaco-dynamic readouts and progression biomarkers for clinical trials aiming for disease modification are insufficient since no endogenous marker reflecting enhanced kinase activity of the most common LRRK2 G2019S mutation has been reported yet in L2PD patients. Employing phospho-/proteomic analyses we assessed the impact that LRRK2 activating mutations had in peripheral blood mononuclear cells (PBMCs) from a LRRK2 clinical cohort from Spain (n=174).

Reward of tactile genital stimulation is sexually equivalent, but mechanistically differentiated in mice.

Gonadal steroid hormones are thought to activate sexual behavior by actions on multiple organ systems, including the nervous system and genitalia. We previously characterized ovarian hormone dependent behavioral and neural responses to clitoral stimulation in female mice. Here we investigate whether sex differences exist in the responses to tactile genital stimulation, and whether these might depend on gonadal androgens.

Laser land leveling technology for paddy production in Vietnam: impact on efficient irrigation and water conservation.

This research investigates the empirical effects of the laser land leveling (LLL) adoption on irrigation water and water efficiency in paddy production in the Mekong Delta region (MDR), using the randomized controlled trial (RCT) approach incorporated into input demand function models. The descriptive analysis highlights the potential for water reuse through farmers' drainage practices. However, the dependence on experiential methods for applying technology in paddy production poses challenges that could compromise long-term sustainability.