The plant endoplasmic reticulum UPRome: A repository and pathway browser for genes involved in signaling networks linked to the endoplasmic reticulum.

The endoplasmic reticulum (ER) houses sensors that respond to environmental stress and underly plants' adaptative responses. These sensors transduce signals that lead to changes in nuclear gene expression. The ER to nuclear signaling pathways are primarily attributed to the unfolded protein response (UPR) and are also integrated with a wide range of development, hormone, immune, and stress signaling pathways.

Depression and Bipolar Support Alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late life.

Objectives: To review progress made during the past decade in late-life mood disorders and to identify areas of unmet need in health care delivery and research.

Participants: The Consensus Development Panel consisted of experts in late-life mood disorders, geriatrics, primary care, mental health and aging policy research, and advocacy.

Evidence: (1) Literature reviews addressing risk factors, prevention, diagnosis, treatment, and delivery of services and (2) opinions and experiences of primary care and mental health care providers, policy analysts, and advocates.

The network trilogy project: linking aging, mental health and health agencies.

There is a striking disparity between the estimated need for mental health care by 18-25% of the nation's elderly, and the minimal utilization of private and publicly funded services by this age cohort. Recognition that the elderly are not well served by existing systems led a trilogy of major Philadelphia aging, mental health, and health organizations to form a partnership for the purpose of improving, expanding, and integrating service delivery for a segment of the population which has been overlooked. A training model was devised to overcome the organizational isolation of agencies serving mutual clients with interrelated problems.