Hospitalisation rates for youth living with perinatally acquired HIV in England.

Introduction: Complex challenges amongst ageing cohorts of adolescents and adults living with perinatally acquired HIV (PaHIV) may impact on hospitalisation. We report hospitalisation rates and explored predictive factors for hospitalisation in adolescents and adults (10-35 years) living with PaHIV in England.

Method: Retrospective observational cohort study over a three-year period 2016-2019.

Detection of 10 cases of ceftriaxone-resistant in the United Kingdom, December 2021 to June 2022.

Between December 2021 and June 2022, 10 cases of ceftriaxone-resistant (ST8123; n = 8) were detected in the United Kingdom, compared with nine cases during the previous 6 years. Most of these cases were associated with travel from the Asia-Pacific region; all were heterosexual people, with most in their 20s. Although all cases were successfully treated, not all partners of cases could be traced, and there is a risk of further transmission of ceftriaxone-resistant gonococcal infection within the UK.

Time trends in contraceptive prescribing in UK primary care 2000-2018: a repeated cross-sectional study.

Background: Over the last 20 years, new contraceptive methods became available and incentives to increase contraceptive uptake were introduced. We aimed to describe temporal trends in non-barrier contraceptive prescribing in UK primary care for the period 2000-2018.

Methods: A repeated cross-sectional study using patient data from the IQVIA Medical Research Data (IMRD) database.

Use of contraceptives and risk of inflammatory bowel disease: a nested case-control study.

Background: How contraceptive formulation, dose, duration of therapy and mode of delivery affects the risk of inflammatory bowel disease (IBD) is poorly described.

Aim: To examine associations between types of hormonal contraception and development of IBD.

Methods: This was a nested case-control study using IQVIA Medical Research Data.

Psychotic disorders in young adults with perinatally acquired HIV: a UK case series.

Background: Increasing numbers of children with perinatally acquired HIV (PaHIV) are transitioning into adult care. People living with behaviourally acquired HIV are known to be at more risk of psychosis than uninfected peers. Young adults living with PaHIV face numerous risk factors; biological: lifelong exposure to a neurotrophic virus, antiretroviral medication and immune dysfunction during brain development, and environmental; social deprivation, ethnicity-related discrimination, and migration-related issues.