Publications by authors named "T Palotie"
Objective: Temporomandibular joint (TMJ) arthritis is a common finding in juvenile idiopathic arthritis (JIA) patients. TMJ arthritis can cause significant disturbances in TMJ function and growth without treatment. Our aim was to evaluate the effectiveness of medical treatments used to manage TMJ arthritis and how to evaluate the outcome of the treatment.
View Article and Find Full Text PDFSleep bruxism (SB) affects a considerable part of the population and is associated with neuroticism, stress, and anxiety in various studies. However, the causal mechanisms between neuroticism and SB have not been examined. Understanding the reasons for SB is important as understanding bruxism may allow improved comprehensive management of the disorders and comorbidities related to it.
View Article and Find Full Text PDFAlthough patients with obstructive sleep apnea (OSA) have a higher risk for coronavirus disease (COVID-19) hospitalization, the causal relationship has remained unexplored. To understand the causal relationship between OSA and COVID-19 by leveraging data from vaccination and electronic health records, genetic risk factors from genome-wide association studies, and Mendelian randomization. We elucidated genetic risk factors for OSA using FinnGen (total = 377,277), performing genome-wide association.
View Article and Find Full Text PDFAim: The aim of this study was to retrospectively investigate the risk factors and their association on bimaxillary osteotomies to be able to improve patient selection and bimaxillary osteotomy planning.
Material And Methods: Patients treated with a bimaxillary osteotomy were included in the study. The complications were collected retrospectively from the patient data records.
Article Synopsis
- Sleep bruxism (SB) can lead to dental damage, headaches, and pain that disrupt both sleep and daily life, prompting a study to explore its biological mechanisms and related health issues.
- Using data from over 377,000 individuals, the study identified 12,297 cases of SB and examined associations with risk factors and comorbidities through logistic regression and genetic analysis.
- The analysis found a significant genetic association linked to the MYO3B gene and noted connections between SB and various health issues, highlighting its relevance across multiple health domains and providing valuable data for future research.