Publications by authors named "T P Thomopoulos"
Purpose: Revisional bariatric surgery (RBS) has flourished during the last decades in many countries, due to suboptimal weight loss or long-term complications of primary bariatric surgery. Restrictive procedures, and in particular sleeve gastrectomy (SG), although widely performed as primary bariatric surgery, seems particularly prone to need surgical revision for the above-mentioned reasons during long-term follow-up. The aim of this systematic review was to compare the long-term (5-year) safety and efficacy between Roux-en-Y gastric bypass (RYGB) and single anastomosis duodeno-ileal bypass (SADI) after 'failed' SG.
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- Multiple myeloma is a type of cancer affecting plasma cells, with an incidence of 3-4 per 100,000 in Caucasians and is the second most common blood cancer after non-Hodgkin lymphoma.
- A case study is presented of a 62-year-old woman with a history of multiple myeloma who experienced vision problems and other symptoms, leading to the discovery of ocular involvement as a sign of cancer recurrence.
- Despite no abnormalities found in MRI, the elevated intracranial pressure and presence of cancer cells in the spinal fluid confirmed the diagnosis, and after treatment, her vision improved significantly.
Direct oral anticoagulants (DOACs) are the standard treatment for thromboembolic protection in atrial fibrillation (AF) patients. Epigenetic modifications, such as DNA methylation and microRNAs, have emerged as potential biomarkers of AF. The epigenetics of DOACs is still an understudied field.
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- Acute Myeloid Leukemia (AML) is a serious illness that often needs strong treatments called chemotherapy, but sometimes these treatments don't work well enough.
- Researchers studied how certain genes related to DNA damage respond in AML cells after chemotherapy using two different medicines: Idarubicin and Cytarabine.
- They found that a gene called PPP1R15A is important for helping cells recover from stress, and when they turned off this gene, the cancer cells didn't survive as well when treated with the chemotherapy, suggesting a way to make the treatment more effective.