A Physics-Based Computational Forward Model for Efficient Image Reconstruction in Magnetic Particle Imaging.

This article derives and implements a computational physics model for model-based image reconstruction in magnetic particle imaging (MPI) applications. To our knowledge, this is the first ever computationally tractable model-based image reconstruction in MPI, which is neither constructed from calibration or simulation experiments or limited to specific scan acquisition geometries. The derived model results in a system constructed from a series of fast linear transforms, each of which incorporate the individual components from the paramagnetic model.

On the partial volume effect in magnetic particle imaging.

Magnetic particle imaging (MPI) is an emerging tomographic 'hot spot' imaging modality with potential to visualize superparamagnetic iron oxide nanoparticle tracer distributions with high sensitivity and quantitative accuracy. MPI shares many similarities with positron emission tomography (PET), where the partial volume effect (PVE) can result in signal under- and over-quantification due to spill-over of signal arising from limited resolution. While the PVE has been alluded to in the MPI literature it has not been previously studied nor characterized.

Integrating Text Structure Instruction in Science Education: A Design-Based Study.

Integrated science-and-literacy programs have proven to positively affect both language proficiency and science knowledge. Because making connections is important in both text comprehension and understanding the disciplinary core ideas taught in science, it seems worthwhile to explore the potential of integrating text structure instruction in science education. Therefore, we conducted a design-based research (DBR) in collaboration with teachers in the upper levels of primary education in the Netherlands.

Gastrointestinal cancer incidence after lung transplantation in sarcoidosis patients.

Background: The risk of gastrointestinal (GI) cancer after lung transplantation (LTx) in sarcoidosis patients is not well defined. Given the cancer risks linked to sarcoidosis and organ transplantation, this study investigated the incidence of GI malignancies (DNM), comparing LTx recipients with sarcoidosis or idiopathic pulmonary fibrosis (IPF).

Methods: We analyzed data from the United Network for Organ Sharing registry, including adults with sarcoidosis or IPF who underwent LTx between May 2005 and December 2018.