Publications by authors named "T P Pinchuk"

Background: QRS fragmentation (fQRS) represents a marker of local myocardial fibrosis, especially in patients with CAD (coronary artery disease). However, little is known about the association between fQRS and the severity of coronary atherosclerosis as defined by the Gensini score.

Objective: To identify the angiographic and echocardiographic characteristics of patients with suspected CAD depending on the location and extent of fQRS.

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Now there is a relevant development of the new biomarkers capable to serve as the instrument of early diagnostics of a disease for the purpose of selection of a pharmacotherapy and further monitoring of its efficiency. Galektin-3 is the atypical representative of the family of galektin. Its participation in fibrosis, remodeling of heart, the immunologic answer and inflammatory reactions are shown.

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Aim: to improve the results of radical cystectomy by optimization of patient preparation for surgery and early postoperative care.

Materials And Methods: A total of 136 patients who underwent radical cystectomy and either orthotopic ileal neobladder or ileal conduit formation were included in the study. Brikkers operation was performed in 92 patients (76% men and 24% women) aged from 39 to 83 years, while in 44 patients (97.

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Aim: To assess an efficacy of diagnostic and curative bronchoscopy in patients with purulent-destructive pulmonary diseases.

Material And Methods: Diagnosis and treatment of 34 patients with purulent-destructive pulmonary diseases including small-focal destruction (14) and lung abscesses (19) were analyzed. 33 patients underwent diagnostic fibrobronchoscopy (FBS) with brush and transbronchial biopsy.

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Aim: To analyze long-term own experience of NPE treatment in view of evolution of surgical sanitation of pleural cavity.

Material And Methods: The analysis included 5115 patients with NPE for the last 39 years (1977-2015). Morbidity, features of microflora of purulent exudate, changes in the structure of surgical methods were assessed.

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