Publications by authors named "T P Nikolopoulos"

Introduction: This study aimed to investigate the relationship between preoperative fine needle aspiration cytology (FNAC) for parotid tumors and the level of surgical training among residents, as well as to further elucidate its effectiveness as a diagnostic tool in the hands of the treating physician.

Materials And Methods: Surgical records from patients who underwent parotid surgery between 2014 and 2022 were retrieved. Residents reported their perceived level of training duringthese procedures.

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Article Synopsis
  • Malignant otitis externa (MOE) is a serious condition often linked to fungi, especially in people with weakened immune systems, prompting a review of fungal cases (FMOE) among patients.
  • The study analyzed 10 articles covering 197 patients, mostly older adults (average age 65.9 years), highlighting that a significant number (78.7%) had conditions like diabetes or cancer.
  • Most patients received conservative treatment focusing on antifungals like itraconazole, with a notable 4% mortality rate attributed to factors such as late diagnosis and cranial nerve issues, suggesting that early antifungal treatment could enhance patient outcomes.
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Screen exposure has both negative and positive effects on the level of language skills a child acquires. The purpose of this review is to address current literature on the possible relationship between unsupervised screen exposure and language development in children and to provide recommendations to caregivers regarding screen exposure of children, taking into consideration the possible effects. A scoping review was conducted using the PubMed/MEDLINE (Medical Literature Analysis and Retrieval System Online) database.

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Tumors located in the nasal cavity, paranasal sinuses and the skull base comprise a wide range of histologic subtypes. Among them, neuroendocrine and undifferentiated tumors are rare but noteworthy, because of their distinctive features, aggressive nature, and diagnostic complexities. A literature search was conducted in the PubMed/MEDLINE and the Scopus databases from 2019 until inception.

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Article Synopsis
  • Proteus syndrome (PS) is a rare genetic disorder caused by mutations in the AKT1 or PTEN genes, leading to uneven tissue growth, while sinonasal neuroendocrine carcinomas (SNEC) are extremely rare tumors found in the nasal and ethmoid cavities.
  • A 35-year-old PS patient had a successful surgical removal of a well-differentiated SNEC obstructing his nasal cavity, illustrating the importance of teamwork among healthcare professionals to ensure safe airway management and effective treatment.
  • This case represents the first report of SNEC in a PS patient, suggesting a potential link between the conditions due to shared genetic pathways involving AKT1 variants.
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