A Latent Class Analysis of Resilience and Its Relationship With Care Burden and Psychological Distress in Family Caregivers of Older Adults With Disability.

Given the challenging circumstances of aging with disability, family caregivers (FGs) face significant strain. Resilience, however, is a crucial protective factor against adverse caregiving outcomes. The study thus aimed to determine the latent classes of resilience among FGs and examine how these classes are related to care burden and psychological distress.

Polylactic acid electrospun membranes coated with chiral hierarchical-structured hydroxyapatite nanoplates promote tendon healing based on a macrophage-homeostatic modulation strategy.

Tendon injury is a common and challenging problem in the motor system that lacks an effective treatment, affecting daily activities and lowering the quality of life. Limited tendon regenerative capability and immune microenvironment dyshomeostasis are considered the leading causes hindering tendon repair. The chirality of biomaterials was proved to dictate immune microenvironment and dramatically affect tissue repair.

Assessment of Externally Prestressed Beams with FRP Rebars Considering Bond-Slip Effects.

This paper presents detailed numerical modeling of externally prestressed concrete (EPC) beams with fiber-reinforced polymer (FRP) rebars. Particular attention is paid to the bond-slip interactions between FRP rebars and concrete. A refined 3D finite element model (FEM) incorporating a script describing the bond-slip of FRP rebars and concrete is developed in ABAQUS.

Chirality Regulates Bone Regeneration through Mechanoresponse and Immunoregulation.

As an omnipresent occurrence in the natural world, chirality plays a crucial role in numerous biological and physiological processes. Therefore, incorporation of chirality into biointerface materials has been emerging as a research hotspot in the development of regenerative biomaterials. Nevertheless, how chiral biointerface materials interact with biological organisms remains poorly understood.

Development of a Multifunctional Antimicrobial Peptide for Marine Antifouling by Theoretical Calculations and Experimental Approaches.

Marine biofouling poses significant challenges to the economy, safety, and reliability of marine infrastructure. While antimicrobial peptides (AMPs) have emerged as green and efficient antifouling agents, their single functionality and the complexity of preparing antifouling surfaces remain key challenges. This study introduces a multifunctional AMP with combined adhesion and antimicrobial properties, derived from 3,4-dihydroxy-l-phenylalanine (DOPA) and IP12 (sequence IRLRWRWKWPWP).