Background: Postprandial glucose concentration 1-h (1 h-PG) after an oral glucose tolerance test (OGTT) has similar or superior performance to 2 h-PG in predicting type-2 diabetes mellitus (T2DM) in several populations, and is simpler to obtain in clinical practice. However, studies in Asians are scarce. We investigated the utility of elevated baseline 1 h-PG in predicting T2DM incidence within three years, and its relationship with β-cell function in 1250 non-diabetic Asian participants.
View Article and Find Full Text PDFBackground: Serum (plasma) creatinine and cystatin C are widely used in pediatric clinical practice to assess glomerular filtration rate. Both markers have limitations due to the low index of individuality, which affects the clinical sensitivity of population-based reference intervals, especially when wide age ranges are considered. This study aimed to establish age-related reference intervals for plasma cystatin C and creatinine in Vietnamese children.
View Article and Find Full Text PDFThis 61-minute webcast features a conversation about "Pulmonary Embolism"-the focus of Issue 20.3. Hosted by the issue's editors, the discussion engages the authors on emerging themes and lessons learned while researching and writing the articles.
View Article and Find Full Text PDFWe present an iron-photocatalyzed decarboxylative alkylation strategy involving carboxylic acids and Morita-Baylis-Hillman (MBH) acetates to synthesize -type tri- and tetrasubstituted alkenes with moderate to excellent stereoselectivity (/ ratio up to >19:1). This method is applicable to a broad range of structurally diverse primary, secondary, and tertiary alkyl carboxylic acids, as well as complex pharmaceutical and natural carboxylic acids, achieving efficient alkylation of various MBH acetates under mild conditions (>60 examples, with yields up to 96%). This approach offers a powerful strategy for streamlined alkylation.
View Article and Find Full Text PDFThe effects of incorporating Illipe nut into the diet of pigs, in replacement of yellow maize, on their growth performance and meat quality was investigated in a 60 days feeding trial. Twenty-four male pigs were divided into two treatments and fed diets with 0% (T1) or 15% (T2) Illipe nut inclusion. Feed intake, live weight (LW) and backfat thickness (BFT) were taken and used to calculate average daily feed intake (ADFI), average daily gain (ADG), feed conversion ratio (FCR) and increase in backfat (IBF).
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