Publications by authors named "T P Lemmens"
Article Synopsis
- This study analyzes how different platelet collagen receptors (GPVI, α2β1, and GPIb-IX-V) interact with various sources of collagen, impacting platelet activation and thrombus formation.
- Ethical collagens tested include type I collagen from equine tendon, rat tail, and acid-soluble collagen from human umbilical cord.
- The results show varied reliance on receptors for platelet aggregation depending on the collagen type, with GPVI playing a crucial role in reducing thrombus parameters when inhibited, demonstrating that collective receptor interactions influence platelet behavior on different collagen surfaces.
Endothelialized in vitro models for cardiovascular disease have contributed greatly to our current understanding of the complex molecular mechanisms underlying thrombosis. To further elucidate these mechanisms, it is important to consider which fundamental aspects to incorporate into an in vitro model. In this review, we will focus on the design of in vitro endothelialized models of thrombosis.
View Article and Find Full Text PDFThe realities of Medical Assistance in Dying in Canada - CORRIGENDUM.
Palliat Support Care
October 2023