Isolation and Characterization of Homologically Expressed Methanol Dehydrogenase from AM1 for the Development of Bioelectrocatalytical Systems.

(Ca)-dependent pyrroloquinolinequinone (PQQ)-dependent methanol dehydrogenase (MDH) (EC: 1.1.2.

Pattern of chromosomal aberrations persisting over 30 years in a Chernobyl Nuclear Power Plant accident survivor: study using mFISH.

The long-term in vivo cytogenetic effects of high-dose radiation exposure can be traced in accidentally irradiated persons, and particularly useful for developing strategies of monitoring and therapy of such patients, as well as for elucidating the fundamental aspects of hematopoiesis and radiobiology. Using 24-color fluorescent in situ hybridization (mFISH), we analysed the frequency and the spectrum of chromosomal aberrations (CA) in peripheral blood lymphocytes of the Chernobyl Nuclear Power Plant (NPP) accident victim 30, 31, 32 and 33 years after acute accidental exposure to high-dose gamma radiation of the whole body. Totally, 993 metaphase cells were analyzed (or 219, 272, 258, 244 cells each year), of which 297 were aberrant.

[The Traumatogenic Factors of Life-Style of Rural Population].

The article substantiates actuality of problem, presents study methodology and classification of leading traumatogenic factors of life-style of rural population. The results of medical social monitoring were used as a basis for ranking degree of evidence of traumatogenic factors impacting on population health in rural district. The study established a high level of prevalence of traumatogenic factors in population of rural district.

Clonal chromosomal and genomic instability during human multipotent mesenchymal stromal cells long-term culture.

Background Aims: Spontaneous mutagenesis often leads to appearance of genetic changes in cells. Although human multipotent mesenchymal stromal cells (hMSC) are considered as genetically stable, there is a risk of genomic and structural chromosome instability and, therefore, side effects of cell therapy associated with long-term effects. In this study, the karyotype, genetic variability and clone formation analyses have been carried out in the long-term culture MSC from human gingival mucosa.

[The problems of formation of competence of personnel of psychiatric service].

The article considers the category of competence of medical personnel of psychiatric service. The characteristics of focusing on professional activities in-psychiatry are analyzed. The problems of formation of professional competence of psychiatrists are considered.