Publications by authors named "T P Hutchinson"
Charity Scott was a professor of health law at Georgia State University College of Law, the founding director of the College of Law's Center for Law, Health, and Society, and co-founder of the Health Law Partnership (HeLP) at Georgia State. She is an iconic figure in her adopted hometown of Atlanta and certainly one of the most important scholars in the history of the health law field, justly celebrated for her teaching, her innovation, her commitment to interdisciplinary work, and for her compassion and love for others. She was also a dear friend of mine.
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- Tumor Treating Fields (TTFields) use low-intensity electric fields to treat various cancers, including glioblastoma (GBM), but cancer cells can develop resistance to this treatment.
- Research identified a regulatory mechanism involving the prostaglandin E receptor 3 (EP3) and the transcription factor zinc finger 488 (ZNF488) that promotes resistance by aiding the self-renewal of glioma stem-like cells (GSC).
- Targeting either EP3 or ZNF488 re-sensitized resistant GSC to TTFields, suggesting that inhibiting this EP3-ZNF488 axis could prevent or reverse treatment resistance in GBM and other cancers.
We describe the details of a digital holographic microscopy diagnostic capable of quantifying both the topography and velocity of a km/s object with adjustable temporal sensitivity. This technique involves spatially multiplexing a double pulse reflected from a target with reference beams of precisely known temporal separation.
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