Publications by authors named "T P GOLDSTEIN"
Evidence suggests that bats are important hosts of filoviruses, yet the specific species involved remain largely unidentified. Niemann-Pick C1 (NPC1) is an essential entry receptor, with amino acid variations influencing viral susceptibility and species-specific tropism. Herein, we conducted combinatorial binding studies with seven filovirus glycoproteins (GPs) and NPC1 orthologs from 81 bat species.
View Article and Find Full Text PDFProlactin levels have been shown to influence metabolic outcomes, including insulin resistance. Metformin is known to be beneficial in polycystic ovary syndrome (PCOS) patients. PCOS women might react differently to metformin treatment depending on their baseline prolactin levels.
View Article and Find Full Text PDFObjective: Autologous rib harvest with manual framework production is the current gold standard for microtia reconstruction. Recent clinical success with implantation of cadaveric costal cartilage grafts opens the possibility of point of care auricular framework production. This paper assesses the feasibility and efficiency of 3D milling of cadaveric costal cartilage for auricular framework production.
View Article and Find Full Text PDFArticle Synopsis
- Instability after total hip arthroplasty (THA) is a key reason for needing revision surgeries, highlighting the importance of achieving stability through different femoral systems.
- The study used Autodesk Fusion 360 software to simulate and analyze how various head and neck sizes affect the arc of motion (AOM) and jump distances (JDs) in THA and dual mobility systems.
- Results showed that while larger head sizes generally increase AOM, benefits plateau after 36 mm, and using modern polyethylene liners can enhance stability; thus, choosing between THA and dual mobility involves weighing minimal gains in head size against increased stability with larger heads.
Article Synopsis
- The study aimed to evaluate the feasibility, acceptability, and effectiveness of a Sleep Promotion Program (SPP) for adolescents who don't get enough sleep.
- The pilot trial involved 44 adolescents, split between those who continued the program for two months and those who only received monitoring initially; results showed an 8.5% dropout rate and high satisfaction with care.
- The findings indicated that participants in the SPP group significantly increased their total sleep time during the first month but experienced a decrease in the second month, highlighting the program's initial success but also potential sustainability concerns.