Publications by authors named "T P Eagan"
Background: Information on the management of non-tuberculous mycobacterial (NTM) lung infection and disease is scarce. The aim of this study was to investigate the trends in NTM lung infections, and the factors associated with the initiation of treatment and treatment outcomes.
Methods: A retrospective analysis was carried out on patient medical records from Haukeland University Hospital, Bergen, Norway, from 2000 to 2021.
Current microbial diagnostics for pleural infections are insufficient. Studies using 16S targeted next-generation sequencing report that only 10%-16% of bacteria present are cultured and that 50%-78% of pleural fluids containing relevant microbial DNA remain culture negative. As a rapid diagnostic alternative suitable for clinical laboratories, we wanted to explore a PCR-based approach.
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- The study examines the link between malnutrition and all-cause mortality in hospitalized patients using the Global Leadership Initiative on Malnutrition (GLIM) criteria.
- Out of 326 patients, a 17% mortality rate was observed over two years, with malnutrition being linked to a higher risk of death even after adjusting for age, sex, and other health conditions.
- The strongest association was found with severe malnutrition, which had a hazard ratio of 2.73, indicating that patients with severe malnutrition were significantly more likely to die within the two-year follow-up period.