Publications by authors named "T P Butler"
Objective: Investigate the treatment patterns and prescribers of stimulants for attention deficit hyperactivity disorder (ADHD) in young people in New South Wales (NSW).
Method: Longitudinal cohort study of persons born after 1983 and prescribed stimulants for ADHD as per the NSW Ministry of Health Controlled Drugs Data Collection. Results were analyzed descriptively: a) treatment prevalence by year; age; sex; b) speciality of prescribers over time; c) rate of transition from paediatrics to adult psychiatry.
Benzene reduction by molecular complexes remains an important synthetic challenge, requiring harsh reaction conditions involving group I metals. Reductions of benzene, to date, typically result in a loss of aromaticity, although the benzene tetra-anion, a 10π-electron system, has been calculated to be stable and aromatic. Due to the lack of sufficiently potent reductants, four-electron reduction of benzene usually requires the use of group I metals.
View Article and Find Full Text PDFOur review summarizes the diagnostic accuracy of plasma and cerebrospinal fluid (CSF) phosphorylated tau 217 (p-tau217) in detecting amyloid and tau pathology on positron emission tomography (PET). We systematically reviewed studies that reported the diagnostic accuracy of plasma and CSF p-tau217, searching MEDLINE/PubMed, Scopus, and Web of Science through August 2024. The accuracy of p-tau217 in predicting amyloid and tau pathology on PET was evaluated in 30 studies.
View Article and Find Full Text PDFArticle Synopsis
- Late-onset psychosis (LOP) is a complex and poorly understood condition that could stem from late-onset schizophrenia or Alzheimer's disease, making accurate diagnosis crucial for effective treatment.
- * This study used structural MRI data from 699 healthy individuals and 469 patients with schizophrenia or Alzheimer's to employ data-driven techniques, specifically K-means clustering, to differentiate between these conditions.
- * Findings indicated that structural differences, such as larger right putamen volumes in schizophrenia patients, could help in distinguishing between AD and SCZ, highlighting the need for better diagnostic tools for LOP.