Publications by authors named "T P Agrawal"
Diabetic Ketoacidosis in Pregnancy: A Systematic Review of the Reported Cases.
Clin Med Insights Endocrinol Diabetes
January 2025
Background: Diabetic ketoacidosis (DKA) is a rare but serious complication that can develop during pregnancy, with up to 30% of patients presenting with euglycemia, making prompt recognition challenging. It is associated with increased perinatal mortality rates, although the exact risk of maternal mortality remains unclear. The purpose of this systematic review was to examine the available literature and provide an overview of reported cases of DKA during pregnancy.
View Article and Find Full Text PDFCancer cells produce extracellular vesicles (EVs) coated with an anionic sugar polymer, hyaluronan (HA), in the extracellular matrix. Hyaluronan is an established cancer biomarker in several cancer types. In this work, we thoroughly investigated the electrical properties of HA-coated EVs using advanced scanning probe microscopy (SPM) based nanoelectrical modes, which include EFM (electrostatic force microscopy), KPFM (Kelvin probe force microscopy), PFM (piezoresponse force microscopy) and C-AFM (conductive atomic force microscopy).
View Article and Find Full Text PDFArticle Synopsis
- This study focuses on evaluating two patient-reported outcome measures for people with non-small cell lung cancer (NSCLC), specifically the PROMIS Physical Function short form and the NSCLC Symptom Assessment Questionnaire.
- Data were derived from two clinical trials involving a total of 915 participants, assessing the reliability, validity, and thresholds for meaningful changes in these measures.
- The findings showed that both measures are reliable and valid for clinical use, with specific thresholds identified for meaningful changes: a decrease of 6-7 points for PROMIS PF-SF indicating worsening physical function and an increase of 2-3 points for NSCLC-SAQ indicating worsening symptoms.
Article Synopsis
- - Chikungunya is a viral infection mainly spread by mosquito bites, known for causing high fever and joint pain.
- - Although eye-related issues aren't frequent with chikungunya, this report highlights a case of a 60-year-old woman who experienced left abducens nerve palsy due to the infection.
- - Treatment involved five days of intravenous steroids followed by oral steroids, leading to significant improvement in her condition within two weeks.