Publications by authors named "T Otani"
Systemic lupus erythematosus (SLE) is a typical autoimmune disease; although severe disease and refractoriness to existing therapies are still experienced, the number of cases resistant to remission induction has decreased with the establishment of various therapies. However, improving long-term prognosis remains a challenge due to the unavoidable prolonged use of non-selective glucocorticoids. To investigate the additional effect of belimumab in the chronic phase, we included 28 of 46 patients with SLE who were initiated on belimumab between January 2018 and October 2022 for glucocorticoid reduction.
View Article and Find Full Text PDFObjectives: Colorectal endoscopic submucosal dissection (ESD) for large tumors is spreading worldwide. Gastric cancer (GC) sometimes occurs after colorectal ESD. However, its status including frequency and risk factors have not been examined well.
View Article and Find Full Text PDFWe examine the conditions for the emergence of self-organized criticality in the Olami-Feder-Christensen model by introducing a single defect under periodic boundary conditions. Our findings reveal that strong localized energy dissipation is crucial for self-organized criticality emergence, while weak localized or global energy dissipation leads to its disappearance in this model. Furthermore, slight dissipation perturbations to a system in a self-organized criticality reveal a novel state characterized by a limit cycle of distinct configurations.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the relationship between hyoid bone (HB) movement and tongue kinematics, particularly during forward tongue protrusion, which is important for speech.
- While HB movement affects various functions like swallowing and breathing, it hasn't been thoroughly examined in tongue modeling, especially outside of swallowing studies.
- Ultrasound imaging showed that HB moved anterosuperiorly during tongue protrusion, and simulations indicated that this movement significantly enhances the anterior displacement of the tongue tip when compared to movements without HB involvement.
Background: The optimal timing and selection for blood culture collection in patients with acute cholangitis remains unclear. The relationship between common bile duct (CBD) diameter and the incidence of bacteremia in patients with CBD stones was elucidated.
Methods: This single-center retrospective observational study included patients with symptomatic CBD stones who presented to the emergency department between January 2019 and December 2021.