Nuclear localization of NRF2 in stroma of HER2 positive and triple-negative breast cancer.

Breast cancer is one of the leading causes of cancer-related mortality in women. During tumor growth, periods of hypoxia are followed by reoxygenation due to neovascularisation leading to disturbed redox homeostasis. ROS (Reactive Oxygen Species) produced under hypoxia activate HIF1α.

Comparison of Surgisis, Vypro II and TiMesh in contaminated and clean field.

Purpose: The study aimed to evaluate the histologic properties and infection resistance of three different mesh materials in a rat model.

Methods: Each mesh, in both infectious (n = 96) and non-infectious groups (n = 270), was positioned both in sublay (preperitoneally) and onlay (subcutaneously) locations. Properties of the biological (Surgisis; Cook Surgical), composite, partially resorbing (Vypro II mesh; Ethicon) and non-resorbing (TiMesh; GFE Medizintechnik GmbH) mesh were evaluated and compared.

Evaluation of breath alcohol analysers by comparison of breath and blood alcohol concentrations.

The main goal of this study was to determine the reliability of hand-held breath alcohol analysers currently approved for roadside screening of traffic offenders. The first part of the study included a retrospective data analysis of 714 offence records collected in 2011. Blood alcohol concentrations (BAC) obtained from the offenders 0-303 min after the police had screened them for breath alcohol concentration (BrAC) were back-calculated (cBAC) to assess the accuracy of breathalyser screening.

Influence of hormonal status on thermography findings in breast cancer.

The aim of this study was to investigate the association of infrared imaging findings and hormone receptor (estrogen and progesterone) status in breast cancers. The study was carried out at Department of Surgical Oncology and Department of Pathology, Sestre milosrdnice University Hospital Center, in collaboration with licensed infrared thermography experts. The study involved 75 female patients with invasive breast tumors.

[Epidemiology of invasive breast cancer according to histopathologic and immunohistochemistry prognostic factors].

The aim of this study was to analyze the TNM classification factors of invasive breast cancer that can be affected by the national program for early detection of breast cancer in the Republic of Croatia. The other analyzed factors related to histology and immunohistochemistry have no such impact as they are related to biological behavior and aggressiveness of malignant breast tumors, thus providing useful predictive and prognostic information. The study was performed at Department of Oncologic Surgery, Sestre milosrdnice University Hospital Center, and included 75 patients surgically treated for invasive breast cancer during the period of one month in 2011, mean age 64 +/- 11.