Publications by authors named "T Okech"

Article Synopsis
  • End-stage kidney disease (ESKD) requires kidney replacement therapies (KRTs) like kidney transplantation (KT), hemodialysis (HD), and peritoneal dialysis (PD) for survival, but access to these treatments is often limited due to high costs.
  • A systematic review analyzed economic evaluations and comparisons of KRTs across thirteen studies, revealing that KT was generally the most cost-effective option, while HD was the least effective and most expensive compared to PD.
  • The review emphasizes that enhancing access to both KT and PD could significantly improve treatment options for ESKD patients, especially in high-income countries.
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Current treatment outcome of patients with glioblastoma (GBM) remains poor. Following standard therapy, recurrence is universal with limited survival. Tumors from 173 GBM patients are analysed for somatic mutations to generate a personalized peptide vaccine targeting tumor-specific neoantigens.

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Objectives: To estimate the modified societal costs of cervical cancer treatment in Kenya; and to compare the modified societal costs of treatment for pre-cancerous cervical lesions integrated into same-day HIV care compared to "non-integrated" treatment when the services are not coordinated on the same day.

Materials And Methods: A micro-costing study was conducted at Coptic Hope Center for Infectious Diseases and Kenyatta National Hospital from July 1-October 31, 2014. Interviews were conducted with 54 patients and 23 staff.

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Objective: This study evaluated the potential cost-effectiveness of cervical cancer screening in HIV treatment clinics in Nairobi, Kenya.

Methods: A Markov model was used to project health outcomes and costs of cervical cancer screening and cryotherapy at an HIV clinic in Kenya using cryotherapy without screening, visual inspection with acetic acid (VIA), Papanicolaou smear (Pap), and testing for human papillomavirus (HPV). Direct and indirect medical and non-medical costs were examined from societal and clinic perspectives.

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