Association of trajectories of physical frailty status and incident disability in community-dwelling older adults: A longitudinal study.

Aim: Frailty is a mediator between robustness and functional disability. This study examined the association between remission of frailty and incident disability.

Methods: The present study analyzed longitudinal data from 2601 community-dwelling older adults who were aged ≥65 years (mean age 70.

The Apparent Lack of the Risk of Intussusception Immediately After Rotavirus Vaccination Among Japanese Infants.

Rotavirus vaccines carry a small risk of intussusception mainly 1-7 days after vaccination in the United States of America, Europe, Australia, and Latin America where the background rate of intussusception is relatively low. Such risks are undetectable in Africa and India where the background rate is the lowest. Because few studies were carried out in high-background-rate countries such as Japan, we examined how intussusception occurred in infants living in Akita prefecture, Japan, while the vaccines were sold in the private market.

Coexistence of somatic and psychological symptoms of depression among community-dwelling older adults is associated with the incidence of dementia.

Background: Depression in old age is associated with the incidence of dementia. However, whether a combination of somatic and psychological symptoms influences the risk of dementia has not been fully investigated.

Objective: We aimed to determine the association between the combination of psychological and somatic symptoms of depression and the incidence of dementia.

Association between cardiovascular disease risk and sarcopenia in community-dwelling Japanese older adults.

Aim: Sarcopenia's high prevalence in older adults with cardiovascular disease (CVD) suggests that the risk of comorbidity in sarcopenia might also be increased during the at-risk phase of CVD. However, the relationship between CVD risk and sarcopenia has not been elucidated. Therefore, the purpose of this cross-sectional study was to investigate the association between CVD risk and sarcopenia in community-dwelling Japanese older adults.

Outer-surface adduct formation and selective separation of -type gallated and -type non-gallated catechins using cucurbit[7]uril.

We found that -type gallated and non-gallated catechins form low water solubility outer-surface adducts with cucurbit[7]uril in aqueous solution, with -type gallated catechins showing a higher tendency to precipitate as outer-surface adducts. By exploiting this phenomenon, we achieved the selective separation of -type gallated and non-gallated catechins in solution.