Publications by authors named "T Ogo"
Purpose: Double-tract reconstruction (DTR) is one of the major procedures following proximal gastrectomy (PG) with anti-reflex function for the esophagus. Although many studies demonstrated the feasibility of laparoscopic DTR, there is a lack of research on robotic DTR. We aimed to assess the safety and feasibility of robotic DTR following PG.
View Article and Find Full Text PDFUnlabelled: Inherited antithrombin deficiency is an autosomal dominant thrombophilia, resulting from genetic variations in the serpin family C member 1 (SERPINC1) gene. Antithrombin deficiency increases the risk of venous thromboembolism (VTE) compared to the general population. In this report, a novel missense variant of , c.
View Article and Find Full Text PDFArticle Synopsis
- - Takayasu arteritis (TAK) is a serious condition that affects large blood vessels, leading to issues like blockages and aneurysms; it's primarily treated with glucocorticoids, but new biological drugs like tocilizumab are proving effective.
- - Patients on tocilizumab may face higher surgical complications, such as infection or delayed healing, and typically do not show increased inflammatory markers during infections, making management challenging.
- - There is a lack of guidelines for the best perioperative care for TAK patients needing cardiovascular surgery, but this article proposes a protocol based on recent evidence to help reduce complications in these patients.
Article Synopsis
- The INCREASE trial demonstrated that inhaled treprostinil enhances exercise capacity in patients with pulmonary hypertension linked to interstitial lung disease (PH-ILD), but lacked specific hemodynamic and pharmacokinetic data.
- A new trial in Japan evaluated the drug's effects on hemodynamics, exercise capacity, safety, and pharmacokinetics, administering inhaled treprostinil at escalating doses.
- Results showed a significant reduction in pulmonary vascular resistance and an increase in walking distance over 16 weeks, along with manageable side effects like cough and low blood pressure, indicating the drug's efficacy and safety in this patient group.