Publications by authors named "T O Woods"

The dianion [Fe[(μ-SeCH)NH](CN)(CO)] ([]) is of interest for the preparation of the selenide analog of the active site of the [FeFe]-hydrogenases. The obvious route for its synthesis by cyanation of Fe[(μ-SeCH)NH](CO) () fails for reasons that this paper explains and resolves. We show that CN cleaves Se-C bonds in .

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Proliferative verrucous leukoplakia (PVL) is an aggressive and distinct type of oral precancerous lesion characterized by warty surfaced white plaque diffusely involving oral mucosa. Surgical excision is the treatment of choice. However, PVL has persistent and recurrent growth patterns, requiring multiple surgical procedures.

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The X-Ray Sensor (XRS) has been making full-disk observations of the solar soft X-ray irradiance onboard National Oceanic and Atmospheric Administration's (NOAA) Geostationary Operational Environmental Satellites since 1975. Critical information about solar activity for space weather operations is provided by XRS measurements, such as the classification of solar flare magnitude based on X-ray irradiance level. The GOES-R series of XRS sensors, with the first in the series launched in November 2016, has a completely different instrument design compared to its predecessors, GOES-1 through GOES-15.

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Article Synopsis
  • Recent advancements in aging research and drug discovery connect basic research with clinical applications, aiming to promote healthy longevity in humans.* -
  • The Aging Research and Drug Discovery Meeting in 2023 highlighted key areas such as AI, biomarkers, geroscience, and clinical trials focused on enhancing healthspan.* -
  • The meeting emphasized the importance of combining generative AI with innovative biological technologies to tackle age-related diseases and extend healthy lifespans.*
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A diverse group of RNA viruses have the ability to gain access to the central nervous system (CNS) and cause severe neurological disease. Current treatment for people with this type of infection is generally limited to supportive care. To address the need for reliable antivirals, we utilized a strategy of lethal mutagenesis to limit virus replication.

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