Altered trial-to-trial responses to reward outcomes in KCNMA1 knockout mice during probabilistic learning tasks.

The large-conductance calcium- and voltage-activated potassium (BK) channels, encoded by the KCNMA1 gene, play important roles in neuronal function. Mutations in KCNMA1 have been found in patients with various neurodevelopmental features, including intellectual disability, autism spectrum disorder (ASD), or attention deficit hyperactivity disorder (ADHD). Previous studies of KCNMA1 knockout mice have suggested altered activity patterns and behavioral flexibility, but it remained unclear whether these changes primarily affect immediate behavioral adaptation or longer-term learning processes.

Cooperativeness as a Personality Trait and Its Impact on Cooperative Behavior in Young East Asian Adults Who Synchronized in Casual Conversations.

Cooperation is essential in social life, involving collaborative efforts for mutual benefits. Individual differences in the cooperativeness trait are pivotal in these interactions. A single-group pretest-posttest design was used in this study to determine if Duchenne smiling with gaze and inter-brain synchrony (IBS) during conversation mediates the relationship between cooperativeness and cooperative behavior.

Effect of time delay on performance and timing control in dyadic rhythm coordination using finger tapping.

In musical ensembles, people synchronise with each other despite the presence of time delays such as those related to sound transmission. However, the ways in which time delays in synchronisation are overcome remain unclear. This study aimed to investigate the basic characteristics and mechanism of synchronisation with time delays using a dyadic synchronisation-continuation finger-tapping task with time delays ranging from 0 to 240 ms.

Nonlinear age-related differences in probabilistic learning in mice: A 5-armed bandit task study.

This study explores the impact of aging on reinforcement learning in mice, focusing on changes in learning rates and behavioral strategies. A 5-armed bandit task (5-ABT) and a computational Q-learning model were used to evaluate the positive and negative learning rates and the inverse temperature across three age groups (3, 12, and 18 months). Results showed a significant decline in the negative learning rate of 18-month-old mice, which was not observed for the positive learning rate.

Complete genome sequence of three strains isolated from patients with skin diseases in Japan.

is a member of the human skin microbiota as a commensal organism but could be an important opportunistic pathogen for immunocompromised individuals. Here, we report the complete genome sequence of three . strains isolated from patients with skin diseases.