Publications by authors named "T Nonogaki"
Article Synopsis
- - A 28-year-old pregnant woman developed severe hypertension early in her pregnancy due to a renin-secreting renal tumor, which was a rare cause of hypertension during this stage.
- - After being hospitalized for blood pressure management and diagnosed with a tumor, she underwent a robot-assisted partial nephrectomy at 16 weeks, which eliminated her hypertension.
- - The successful outcome, with the delivery of a healthy baby at 40 weeks, highlighted the importance of early intervention, medication, and careful monitoring for pregnant women experiencing hypertension.
Background & Aims: Data regarding the delivery of nutrition and nutritional infusions to patients with terminal cancer remain limited; therefore, this real-world analysis investigated differences in nutrition delivery and infusion statuses for patients with terminal-stage cancers.
Methods: Patients who had died following hospitalization for more than seven days due to neoplasms between April 2014 and December 2018 were identified using the medical claims database of Japan. Data regarding oral diets, enteral feeding, infusion volumes, and infusion energies were extracted.
Article Synopsis
- A 69-year-old woman had ovarian and uterine mesonephric-like carcinoma alongside endometrioid adenofibroma and underwent surgery for tumor removal.
- Histological analysis showed that both tumors were likely related, sharing a common origin from Müllerian duct and exhibiting the same KRAS G12D mutation, indicating they were monoclonal.
Background & Aims: Few studies have examined the association between mortality and malnutrition diagnosed using the Global Leadership Initiative on Malnutrition (GLIM) criteria for routine nutritional assessment; thus, this association is not well known. We aimed to clarify the association between GLIM-defined malnutrition and mortality in a large population of hospitalized patients.
Methods: In this retrospective cohort study, we enrolled adult patients admitted to Aichi Medical University Hospital between April 2019 and March 2021, who underwent nutritional assessment using the GLIM criteria.
The precise mechanism by which butyrate-producing bacteria in the gut contribute to resistance to respiratory viral infections remains to be elucidated. Here, we describe a gut-lung axis mechanism and report that orally administered Clostridium butyricum (CB) enhances influenza virus infection resistance through upregulation of interferon (IFN)-λ in lung epithelial cells. Gut microbiome-induced ω-3 fatty acid 18-hydroxy eicosapentaenoic acid (18-HEPE) promotes IFN-λ production through the G protein-coupled receptor (GPR)120 and IFN regulatory factor (IRF)-1/-7 activations.
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