Solid-state cultivation of multiple industrial strains of koji mold on different Thai unpolished rice cultivars: biotransformation of phenolic compounds and their effects on antioxidant activity.

Colored rice is abundant in polyphenols, and koji molds have potential for biotransformation. This study aimed to produce Thai-colored rice koji to study its polyphenolic biotransformation. Four industrial koji mold strains: Aspergillus oryzae 6001, A.

New analogs of pochonicine, a potent β--acetylglucosaminidase inhibitor from fungus var. TAMA 87.

Three novel analogs of pochonicine () were isolated from a solid fermentation culture of the fungal strain var. TAMA 87, and their structures were elucidated as 7-deoxypochonicine (), 6-deoxypochonicine (), and 6,7-dideoxypochonicine (). These analogs were found to possess the same stereochemistry as pochonicine.

Aerobic bioconversion of C-glycoside mangiferin into its aglycone norathyriol by an isolated mouse intestinal bacterium.

Norathyriol is an aglycone of a xanthonoid C-glycoside mangiferin that possesses different bioactive properties useful for humans compared to mangiferin. Mangiferin is more readily available in nature than norathyriol; thus, efficient mangiferin conversion into norathyriol is desirable. There are a few reports regarding mangiferin C-deglycosylation because of the C-C bond resistance toward acid, alkaline, and enzyme hydrolysis.

A new asteltoxin analog with insecticidal activity from TAMA 87.

A new asteltoxin analog, named asteltoxin H (), was isolated by the solid-state fermentation of the fungus var. TAMA 87. The chemical structure of was deduced by spectroscopic methods, including 1D and 2D NMR, HRESIMS, and UV-Vis analyses.

Convenient preparation of an antigenic oligosaccharide from white kidney bean powder: A useful plant oligosaccharide for synthesis of immunoactive glycopolymer.

Plant glycoproteins, especially allergenic glycoproteins such as pollen allergens, often carry antigenic N-glycans with α1-3 fucose and/or β1-2 xylose residue(s) on the trimannosyl core structure. We previously reported that one of such antigenic free-form N-glycans, Man3Xyl1Fuc1GlcNAc2 (M3FX) suppressed IL-4 production from Th2 cells of pollinosis patients. For the molecular-level analysis of this immunoactivity, an effective and convenient procedure for large scale preparation of the immunoactive free-form N-glycan and a synthesis of glycopolymers bearing multivalent M3FX has been required.