Publications by authors named "T Nishimoto"
This study presents a novel approach to control "linked property changes" in hydrogels. Specifically, we controlled the swelling behaviour without altering the bulk elastic modulus by grafting polymers selectively into the surface region of the gels, while varying the graft amount.
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- Enhancing the wettability of medical implants is essential for better biocompatibility, and this study explores the use of ozone nanobubble water to improve titanium dental implants' surfaces.
- Immersion in ozone nanobubble water for about 10 minutes changes implants from hydrophobic to superhydrophilic, maintaining this property for over a month, indicating effective surface alteration and cleaning.
- The formation of nanoshells from ozone microbubbles contributes to the long-lasting hydrophilicity of the implants, suggesting that this method could be a promising approach for improving the compatibility of dental implants.
Stepwise Improvement of Cerebral Hemodynamics in Staged Angioplasty for Carotid Artery Stenosis.
Neurol Med Chir (Tokyo)
January 2025
Staged angioplasty (SAP) is used as an alternative to preventing cerebral hyperperfusion syndrome (CHS) after carotid artery stenting (CAS), particularly among patients with compromised cerebral haemodynamics. Although SAP is presumed to prevent CHS by gradually restoring cerebral blood flow (CBF), few studies have examined haemodynamic changes, and none have evaluated CBF during the chronic phase of SAP. In the present study, in addition to the clinical outcome of SAP, we measured both resting CBF and cerebrovascular reactivity (CVR) throughout all stages of SAP, including the chronic phase, using quantitative N-isopropyl-p-[I-123] iodoamphetamine (I-IMP) single-photon emission computed tomography (SPECT) and evaluated the effects of SAP on cerebral haemodynamics.
View Article and Find Full Text PDFImpact of intracranial hypertension and cerebral perfusion pressure on spreading depolarization.
J Cereb Blood Flow Metab
November 2024
Spreading depolarization (SD) develops after stroke and traumatic brain injury and may contribute to secondary brain damage. These diseases are often accompanied by intracranial hypertension, but little is known about the effects of intracranial pressure (ICP) on SD. Here, we study the effect of increased ICP on hemodynamic and metabolic response to SD in rats.
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- Prophylactic surgery for impending fractures in patients with long-bone metastasis is linked to better survival rates compared to those with complete fractures, especially in those deemed intermediate-to-high risk.
- A study of 121 patients revealed lower one-year mortality rates for those with impending fractures, alongside higher rates of home discharge and improved post-operative mobility.
- Results indicated that the type of surgical intervention (nailing vs. hemiarthroplasty) did not significantly affect survival rates among patients with impending fractures.