[Diagnostic value of serum conjugated bile acids in viral hepatitis].

Total and conjugated biliary acids were determined in a lot of 105 subjects, including 15 healthy persons, 60 with acute viral hepatitis, 10 with chronic evolutive hepatitis, 10 with cholecystophaties and dyskinesia and 10 with obstructive jaundice. A marked diminution in the proportion of conjugated biliary acids was found in acute hepatitis and cholecystopathies. Chenodioxycholic and dioxycholic acid increase in acute diseases of the liver, whereas cholic acid increases in obstructive jaundice and chronic hepatitis, with a consecutive almost threefold reduction of th ratio of trihydroxycholanic to dihydroxycholanic acids in acute lesions of the liver cells.