Background: Patent ductus arteriosus (PDA) is a congenital heart defect that requires closure to prevent complications like heart failure and pulmonary hypertension. Catheter-based closure using devices such as the Amplatzer duct occluder is the preferred method due to its minimally invasive nature. However, device embolization is a rare but recognized complication, particularly in small children or high-flow PDAs.
View Article and Find Full Text PDFBackground: Rheumatic heart disease (RHD) continues to pose a significant burden on global health, particularly in socioeconomically disadvantaged populations. We present the case of a 38-year-old woman with severe multivalvular RHD and giant atria, highlighting the challenges and complexities of managing this condition.
Case Presentation: The patient presented with progressively worsening dyspnoea, signs of right heart failure, and severe valvular abnormalities.
A copper-catalyzed direct -Csp-H thiocyanation of free anilines has been developed. This method employs stable and non-toxic ammonium thiocyanate as a thiocyanation source, and -butyl hydroperoxide as the oxidant, enabling the synthesis of -thiocyanated anilines with good yields and broad substrate tolerance. Hitherto, no reports have been found in the literature for the -thiocyanation of aromatic amines, making this reaction an important breakthrough in synthetic organic chemistry.
View Article and Find Full Text PDFPurpose: To compare dose volume parameters of target and organs at risk in vaginal vault brachytherapy using ovoids or cylinder in post-operative endometrial carcinoma.
Material And Methods: The study was done among 25 histologically proven post-operative endometrial carcinoma patients requiring vaginal brachytherapy. All patients underwent both cylinder and ovoids application alternatively on weekly basis.