Publications by authors named "T N Tromp"
Article Synopsis
- The study aimed to evaluate the efficacy of shortening the cast immobilization period for distal radius fractures (DRF) from 3-5 weeks to 1 week followed by gradual mobilization.
- Conducted in various trauma centers, it involved randomly assigning hospitals to either the usual care or the shorter immobilization method, with patients aged 18 to 85 included if they had isolated, non- or minimally displaced DRF.
- Results showed no significant differences in functional outcomes, pain scores, or patient satisfaction between the two groups, suggesting that the shorter immobilization period may be equally effective as the conventional approach.
The economic impact of open lower limb fractures in the Netherlands: a cost-of-illness study.
Eur J Trauma Emerg Surg
October 2024
Purpose: To estimate the one-year sum of direct costs related to open lower limb fracture treatment in an academic setting in the Netherlands. The secondary objective was to estimate the impact of deep infection and nonunion on one-year total direct costs.
Methods: A multi-center, retrospective cost analysis of open lower limb fractures treated in an academic setting in the Netherlands, between 1 January 2017 and 31 December 2018, was conducted.
Diabetes mellitus (DM) is a significant public health issue in Germany, affecting 8 million individuals, with projections suggesting a substantial increase in the following years. Diabetic Foot Syndrome (DFS), leading to mobility issues and limb amputations, challenging healthcare due to resource shortages and the need for specialized care. The EPWUF-KI project seeks to support outpatient caregivers by incorporating artificial intelligence (AI) into DFS wound care, focusing on optimizing treatment and automating documentation.
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- Heterozygous familial hypercholesterolemia (HeFH) is a genetic condition that leads to high cholesterol and increased heart disease risk, though individuals show varying levels of risk for developing coronary artery disease (CAD).
- This study analyzed 1,315 HeFH carriers and their matched noncarrier relatives in the Netherlands, along with data from 151,009 participants in the UK Biobank, to investigate how common DNA variants affect CAD risk through a polygenic score.
- Results demonstrated that HeFH individuals had higher CAD rates than noncarriers, and that a higher polygenic score significantly increased CAD risk, sometimes to levels seen in noncarriers, highlighting the role of genetic factors
Background: Homozygous familial hypercholesterolaemia (HoFH) is a rare genetic disease characterised by extremely high plasma LDL cholesterol from birth, causing atherosclerotic cardiovascular disease at a young age. Lipoprotein apheresis in combination with lipid-lowering drugs effectively reduce LDL cholesterol, but long-term health outcomes of such treatment are unknown. We aimed to investigate the long-term cardiovascular outcomes associated with lipoprotein apheresis initiated in childhood or adolescence.
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