Food & You: A digital cohort on personalized nutrition.

Nutrition is a key contributor to health. Recently, several studies have identified associations between factors such as microbiota composition and health-related responses to dietary intake, raising the potential of personalized nutritional recommendations. To further our understanding of personalized nutrition, detailed individual data must be collected from participants in their day-to-day lives.

[Paediatric digital clinical decision support for global health].

Effective, scalable and sustainable strategies to improve quality of care are needed to address the substantial burden of preventable deaths of children under-five in resource-constrained settings. Clinical decision support systems (CDSS), digital tools which generate recommendations for healthcare providers based on patient-specific information, show promise. By strengthening adherence to evidence-based assessment, diagnosis and management and generating high-quality data, CDSS can improve quality care - care that is effective, safe, people-centered, timely, equitable, integrated and efficient.

[Reasons for the delayed realisation of pregnancy. Results of a questionnaire among women in childbed in the new (east) and old (west) federal states of Germany in 1998-2000].

Background: The number of live births in Germany has decreased by 46.7 % from 1 261 614 in 1960 to 672 675 in 2006. The causes for this are manifold.

2-Naphthylcarbapenems: broad spectrum antibiotics with enhanced potency against MRSA.

A regioisomeric set of 2-naphthylcarbapenems featuring cationic substituents was synthesized. Optimal placement of the cationic group was found to markedly improve activity against methicillin-resistant staphylococci while maintaining a good spectrum of gram-negative activity.

The synthesis of 2-(functionalized methyl)-1 beta-methylcarbapenems.

The synthesis of 1 beta-methylcarbapenems having a ROCH2 substituent at the 2-position is described. Their in vitro antibacterial activity and DHP-I susceptibilities are presented.