Publications by authors named "T N Marion"
Article Synopsis
- This study investigated the postoperative recovery of leg pain and overall health in patients who underwent surgery for radiculopathy over a two-year period.
- It aimed to pinpoint preoperative factors that could predict which patients might have poor recovery outcomes after lumbar discectomy.
- The findings revealed that while most patients (around 88.6% for leg pain and 71.9% for overall outcomes) had positive results, about 11.4% to 28.2% experienced minimal improvement, highlighting the need for predictive models for better clinical decision-making.
Study Design: Retrospective cohort study.
Objectives: The impact of delayed access to operative treatment on patient reported outcomes (PROs) for lumbar degenerative conditions remains unclear. The goal of this study is to evaluate the association between wait times for elective lumbar spine surgery and post-operative PROs.
Background: The coronavirus pandemic highlighted the need for remote patient monitoring to deliver and provide access to patient care and education. A mobile-based app providing interactive tools for patient education and monitoring was piloted at Thunder Bay Regional Health Sciences Centre (TBRHSC) in November 2020. We aimed to examine the platform's impact on postoperative length of stay, hospital readmissions, and emergency department (ED) visits 60 days postsurgery in total hip and knee arthroplasty patients in Northwestern Ontario.
View Article and Find Full Text PDFTripartite-motif protein-56 (TRIM56) positively regulates the induction of type I interferon response via the TLR3 pathway by enhancing IRF3 activation and depends on its C-terminal residues 621-750 for interacting with the adaptor TRIF. However, the precise underlying mechanism and detailed TRIM56 determinants remain unclear. Herein, we show ectopic expression of murine TRIM56 also enhances TLR3-dependent interferon-β promoter activation, suggesting functional conservation.
View Article and Find Full Text PDFIntroduction: Adequate guidelines for treatment of people over 65 years, suffering traumatic thoracolumbar spine fractures without neurologic deficit, are currently lacking.
Research Question: The aim of this study was to systematically review the available literature regarding the outcome of conservative and surgical treatment of thoracolumbar spinal trauma in elderly patients.
Material And Methods: A systematic review according the PRISMA guidelines was performed.