[Indices of cholecystokinin secretion, vegetative regulation of heart rate and anxiety level in patients with a motor dysfunction of the gallbladder].

We examined 36 patients with biliary diseases (14 men and 22 women) at the age of 19-62 (19 patients with chronic non-calculous cholecystitis, 11 patients with cholelithiasis, and 6 patients with gallbladder dysfunctions) as well as 14 practically healthy people from the control group. Methods of the study included dynamic sorbite echography of the gallbladder, determination of serum cholecystokinin by the radioimmunoassay (RIA) as well as examination of variability of the cardiac rate and anxiety level. Patients with a motor dysfunction of the gallbladder suffer from disorders of the correlation between cholecystokinin secretion, the functional state of the vegetative nervous system and the nature of the motor and evacuation function of the gallbladder.

[Effects of mental adaptation on vegetative, hormonal and sensory reactions in preoperative period].

Fifty-seven urological patients whose emotional behavioral reactions were characterized by somatic anxiety caused by mental adaptation were examined under conditions of preoperative emotional stress. On day 5 after admission to hospital the hormonal, autonomic, and sensory responses decreased in patients with previously manifest anxiety, which was due to decrease of anxiety because of appearance of some psychopathological features. Satisfactory hormonal, autonomic, and mental adaptation was observed on day 5 after admission to hospital in patients with moderately expressed anxiety.

[Correlation between the effectiveness of premedication and neuroanatomic protection during surgery with NLA and the initial state of the autonomic nervous system].

The study was performed on 94 urological patients, aged 15 to 78 years, subjected to planned operations. The initial autonomic tone, autonomic reactivity, autonomic maintenance of the activity, ACTH and cortisol content have been investigated in the ward and in the operation room with concomitant premedication with pipolphen in combination with promedol and diazepam in combination with promedol. Tactile and pain thresholds were studied in patients on premedication in the ward and the operation room.