[Transient form of serum albumin in gynecologic cancer].

The frequency of diagnostic errors in examination of 3827 patients with gynecological cancer diseases accounted for 21.6 up to 35%. The conformation of serum albumin in these patients was studied by means of different biochemical assays.

[Use of the physicochemical characteristics of serum albumin for diagnosing ovarian and uterine cancer].

The frequency and causes of diagnostic errors are discussed on the basis of 2,099 case histories of ovarian and uterine tumors. The use of physico-chemical characteristics of serum albumin as an additional means of diagnosis of these diseases in 16 patients and 20 healthy subjects was studied. Patients revealed changes in dispersion of optical rotation of serum albumin which suggest its despiralization.