Publications by authors named "T Myojin"
The 5-aminosalicylic acid (5-ASA) agents are first-line drugs for ulcerative colitis (UC). However, intolerance as well as other issues have been reported for these drugs, making it difficult to sustain this treatment; accordingly, the persistence of 5-ASA is an important indicator of UC treatment strategy. We aimed to analyze the persistence of 5-ASA in patients with UC in Japan.
View Article and Find Full Text PDFAim/introduction: Although immune checkpoint inhibitor-related type 1 diabetes mellitus (ICI-T1DM) is a rare condition, it is of significant concern globally. We aimed to elucidate the precise incidence, risk factors, and impact of ICI-T1DM on survival outcomes.
Materials And Methods: The study is a large retrospective cohort study, performed using the DeSC Japanese administrative claims database comprising 11 million patients.
Evidence of the effectiveness of β-blockers in heart failure (HF) and atrial fibrillation (AF) in a contemporary cohort is controversial. This study investigated the association between the use of β-blockers and prognosis in hospitalized HF patients with and without AF in Japan. Patients hospitalized with the first episode of acute HF were identified from the National Database of Health Insurance Claims and Specific Health Checkups of Japan between April 2014 and March 2021.
View Article and Find Full Text PDFArticle Synopsis
- A study examined the link between changes in estimated glomerular filtration rate (eGFR) and the risk of developing end-stage kidney disease (ESKD) in the general population using data from Japanese health check-ups.
- Researchers analyzed data from over 115,000 individuals who had their eGFR measured three times between 2013 and 2020, discovering that those with a higher coefficient of variation in eGFR (CVeGFR ≥ 8.5%) had a significantly increased risk of ESKD.
- The findings suggest that annual variations in eGFR can indicate a higher risk of ESKD, independent of other traditional risk factors, highlighting the importance of monitoring eGFR in health assessments
Article Synopsis
- - The study explored how neighborhood features, like parks and sidewalks, affect the healthy life expectancy of older adults, focusing on residents in Japan aged 65 and older who are not in long-term care.
- - Results showed that older adults living in areas with accessible parks and sidewalks had a 1.2-year longer healthy life expectancy and were more physically active compared to those without such amenities.
- - The findings suggest that safe, walkable neighborhoods with good recreational facilities can promote physical activity and improve longevity among older adults, pointing to a need for further research on the underlying factors at play.