Publications by authors named "T Muthukumar"
Cordia diffusa K.C. Jacob, known as Sirunaruvili, belonging to the family Boraginaceae, is a rare endemic species.
View Article and Find Full Text PDFStore-operated calcium entry (SOCE) is essential for cellular signaling. Earlier studies of the pyrazole derivative BTP2, an efficient inhibitor SOCE, identified that SOCE blockade suppresses proinflammatory gene expression. The impact of SOCE blockade on gene expression at the whole transcriptome level, however, is unknown.
View Article and Find Full Text PDFPurpose: Estimation of multi-compartment intravoxel 'flow' in in ml/100g/min with multi-b-value diffusion weighted imaging and a multi-Gaussian model in the kidneys.
Theory And Methods: A multi-Gaussian model of intravoxel flow using water transport time to quantify (ml/100g/min) is presented and simulated. Multi-compartment anisotropic DWI signal is simulated with Rician noise and SNR=50 and analyzed with a rigid bi-exponential, a rigid tri-exponential and diffusion spectrum imaging model of intravoxel incoherent motion (spectral diffusion) to study extraction of multi-compartment flow.
Article Synopsis
- Acute rejection (AR) in kidney transplantation can significantly negate the benefits of the procedure and is typically diagnosed through invasive methods like biopsies.
- Researchers developed a noninvasive urinary cell three-gene signature test that can differentiate between different types of AR (T cell-mediated, antibody-mediated, or mixed) and patients with no rejection.
- The study showed that this gene signature effectively distinguished all types of AR from non-rejection cases with high accuracy, suggesting it could be a valuable tool in kidney transplant monitoring.