Publications by authors named "T Muntean"
Phytochemical profiling of antimicrobial and potential antioxidant plant: .
Front Plant Sci
September 2022
Traditional and phytochemical studies have confirmed the richness and diversity of medicinal plants such as (), but more studies are needed to complete its metabolite profiling. The objective of this research was to enhance the metabolomic picture and bioactivity of for better evaluation. Phytochemical analysis was performed by bio-guided protocols and gas chromatography-mass spectrometry (GC/MS).
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- A new LC/MS method for captopril quantification was developed using a straightforward precolumn derivatization technique and validated for human plasma analysis.
- Sample preparation involved protein precipitation and resulted in high recovery rates, with precision and accuracy metrics showing promising results.
- The method demonstrated stability for various conditions and was successfully applied in a pharmacokinetic study involving healthy volunteers taking captopril.
Validation of an HPLC method for the determination of ciprofloxacin in human plasma.
J Pharm Biomed Anal
September 2003
A simple HPLC method with fluorescence detection of ciprofloxacin in human plasma was developed and validated. After protein precipitation, chromatographic separation of ciprofloxacin in plasma was achieved at 35 degrees C with a C18 column and acetonitrile-phosphate mixture, pH 3, as mobile phase. Quantitative determination was performed by fluorimetry after excitation at 278 nm.
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