Publications by authors named "T Munk-Olsen"
Postpartum psychosis is a severe psychiatric condition marked by the abrupt onset of psychosis, mania, or psychotic depression following childbirth. Despite evidence for a strong genetic basis, the roles of common and rare genetic variation remain poorly understood. Leveraging data from Swedish national registers and genomic data from the All of Us Research Program, we estimated family-based heritability at 55% and WGS-based heritability at 37%, with an overrepresentation on the X chromosome.
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- The study investigated adverse neonatal outcomes in children born to mothers with different eating disorders, including anorexia nervosa (AN), bulimia nervosa (BN), and eating disorder not otherwise specified (EDNOS).
- It analyzed data from over 1.5 million births in Denmark from 1991 to 2015, comparing outcomes based on whether the eating disorder diagnosis was recent (within 2 years of conception) or past (over 2 years before conception).
- Findings showed that recent eating disorders, especially AN, were linked to higher risks of low birthweight, small-for-gestational-age, and preterm birth, emphasizing the need for better prevention and monitoring of eating disorders during pregnancy.
Article Synopsis
- Parents of twins have a higher risk of postpartum depression (PPD) compared to parents of singletons, particularly mothers within the first two months after childbirth.
- A study analyzing data from 27,095 twin births and over 1.3 million singleton births found that the immediate risk of PPD for twin mothers peaks at around two months postpartum, while twin fathers show an increased risk later, around six months.
- The findings highlight the need for greater awareness of the mental health challenges facing parents of twins, as their experiences with PPD may differ significantly from those of singleton parents.
Background: Previous studies have indicated associations between maternal mental disorders and adverse birth outcomes; however, these studies mainly focus on certain types of mental disorders, rather than the whole spectrum.
Aims: We aimed to conduct a broad study examining all maternal mental disorder types and adverse neonatal outcomes which is needed to provide a more complete understanding of the associations.
Method: We included 1 132 757 liveborn singletons born between 1997 and 2015 in Denmark.
Background: Personal and family history of psychiatric disorders are key risk factors for postpartum depression (PPD), yet their combined contribution has been understudied.
Objective: To examine personal and family psychiatric history, alone and combined, and their effect on absolute risk and relative risk (RR) of mild/moderate or severe PPD.
Methods: In this cohort study, we used data from 142 064 childbirths with PPD screenings from 2015 to 2021 merged with population registers.