Publications by authors named "T Mora"

Introduction: Existing research does not provide definitive conclusions on the most effective initiatives for preventing malnutrition among older adult residents in nursing homes.

Objective: We aimed to assess whether a nutrition education intervention provided to nursing home managers can improve dietary managerial decisions within nursing homes.

Methods: We performed a multicenter study, where each center was randomized to an intervention or a control group.

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The adaptive immune response relies on T cells that combine phenotypic specialization with diversity of T-cell receptors (TCRs) to recognize a wide range of pathogens. TCRs are acquired and selected during T-cell maturation in the thymus. Characterizing TCR repertoires across individuals and T-cell maturation stages is important for better understanding adaptive immune responses and for developing new diagnostics and therapies.

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The most effective method of preventing influenza infection and complications is through vaccination. However, annual vaccination rates remain low. This study examines the impact of influenza vaccination on healthcare utilisation among the elderly population in Catalonia, Spain.

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Article Synopsis
  • The human immune system continues to develop for several years after birth, affecting how young children respond to infections, such as SARS-CoV-2.
  • Researchers studied T cell responses in children and adults before, during, and after SARS-CoV-2 infection, revealing that younger children (under 5) had a weaker CD4 T cell response compared to older children and adults with mild disease.
  • Following infection, preschool-age children produced similar neutralizing antibodies to adults but had different T cell characteristics and fewer memory B cells, indicating a gradual maturation of their adaptive immune responses.
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B cell receptors (BCRs) play a crucial role in recognizing and fighting foreign antigens. High-throughput sequencing enables in-depth sampling of the BCRs repertoire after immunization. However, only a minor fraction of BCRs actively participate in any given infection.

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