Zellweger Syndrome is a peroxisomal disorder that can lead to elevation of long chain fatty acids and epilepsy, which can be drug resistant. The treatment of drug resistant epilepsy can include the ketogenic diet in appropriately chosen patients. Typically, the ketogenic diet is contraindicated in individuals with defects in fatty acid metabolism because of the diet's reliance on medium and long chain fatty acids.
View Article and Find Full Text PDFThe genus Bleeker, 1857 is revised with the description of a new species collected from the gempylidaen fish (Cuvier, 1832) from the southwestern coast of India. A revised generic diagnosis is provided based on the redescription of the type species. (Schioedte and Meinert, 1883) is here synonymised with Bleeker, 1857 based on the original description.
View Article and Find Full Text PDFDysfunctions of androgen/TGF-β signaling play important roles in prostate tumorigenesis. Prostate Transmembrane Protein Androgen Induced 1 () inhibits androgen and TGF-β signaling via a negative feedback loop. The loss of confers resistance to androgen signaling inhibitors and promotes bone metastasis.
View Article and Find Full Text PDFA correction to this article has been published and is linked from the HTML version of this paper. The error has not been fixed in the paper.
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