Publications by authors named "T Mitsumatsu"
Article Synopsis
- Delta brushes are spontaneous neural activities in preterm infants' brains, linked to the development of subplate neurons.
- This study examined how these delta brushes affect blood flow (haemodynamics) using simultaneous EEG and near-infrared spectroscopy (NIRS) in five preterm infants at different ages.
- The findings revealed that positive responses in blood oxygen levels predominated during these activities, particularly in the temporal regions, suggesting strong connectivity in the developing brain, especially related to the insula.
Article Synopsis
- The study investigates how sleep states and breathing patterns affect functional connectivity (FC) in the brains of preterm infants compared to term infants, focusing on transitions from preterm to term ages.
- Researchers analyzed data from 63 preterm and 44 term infants using electroencephalography and functional near-infrared spectroscopy to compare FC during active and quiet sleep, and how these patterns relate to neurodevelopmental outcomes.
- Results indicated that preterm infants exhibited higher FC in both sleep states, especially during active sleep, and certain patterns of FC were linked to negative neurodevelopmental indicators in these infants.
Article Synopsis
- The study investigates two patients with post-acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) using EEG-fMRI to understand their epileptic foci and brain networks.
- Patient 1 experienced focal seizures with BOLD changes in various brain regions, while Patient 2 had spasms that improved after a surgical procedure called corpus callosotomy, leading to different BOLD responses pre- and post-operation.
- The findings suggest that EEG-fMRI can identify extensive and complex epileptic networks in these patients, and that corpus callosotomy can help manage seizures by disconnecting these networks.
Background: Various factors contribute to the development of infection-related acute encephalopathy (AE) in children, such as infectious agents and chronic underlying disorders. We studied underlying disorders in children with AE to identify predisposing factors of AE.
Methods: We investigated underlying disorders or past histories in patients with two types of AE from the database in the Tokai area of Japan between 2009 and 2022: 204 patients with AE with reduced subcortical diffusion (AED) and 137 with clinically mild encephalopathy with a reversible splenial lesion (MERS).