The electronic behavior of a photosynthetic reaction center monitored by conductive atomic force microscopy.

The conductivity of a photosynthetic reaction center (RC) from Rhodobacter sphaeroides was measured with conductive atomic force microscopy (CAFM) on SAM-modified Au(111) substrates. 2-mercaptoethanol (2ME), 2-mercaptoacetic acid (MAC), 2-mercaptopyridine (2MP) and 4-mercaptopyridine (4MP) were prepared as SAM materials to investigate the stability and morphology of RCs on the substrate by using near-IR absorption spectroscopy and AFM, respectively. The clear presence of the three well known RC near-IR absorption peaks indicates that the RCs were native on the SAM-modified Au(111).

Therapeutic potential of a fully human monoclonal antibody against influenza A virus M2 protein.

Influenza is one of the most prevalent viral diseases in humans. For some high-risk human populations, including the infant, the elderly, and the immunocompromised, who may not benefit from active immunization, passive immunotherapy with antibodies reactive with all influenza A strains may be an alternative. In this study, we characterized several fully human monoclonal antibodies (MAb) reactive with M2e, which were generated from transchromosomic mice engineered to produce fully human antibodies following immunization with a consensus-sequence M2e peptide.

Fabrication of electrochemical transistor based on pi-conjugate polymer Langmuir-Blodgett film.

We fabricated an efficient organic electrochemical transistor (OECT) composed of polymer Langmuir-Blodgett (LB) film. The pi-conjugated polymer LB film, which was constructed from a poly(N-dodecylacrylamide) (pDDA) and poly(3-hexylthiophene) (PHT) mixture, was used as a conduction channel layer to connect source and drain electrodes. The mixed-polymer LB film was characterized using UV-vis spectroscopy, X-ray diffraction (XRD), atomic force microscopy (AFM), and cyclic voltammetry.

Nanoscale actuation of thermoreversible polymer brushes coupled with localized surface plasmon resonance of gold nanoparticles.

This paper describes the fabrication of hybrid nanoassemblies with polymer brushes and gold nanoparticles enabling detection of nanoscale optical changes based on localized surface plasmon resonance. The reversible and thermosensitive nanoscale actuation is achieved by combining stimuli-responsive polymer brushes and gold nanoparticles independently and selectively assembled on substrates. These hybrid nanoassemblies are assembled on numerous substrates and will be applicable for optoelectronics, nanoactuator, and nanosensor applications.

Fabrication of polymer Langmuir-Blodgett films containing regioregular poly(3-hexylthiophene) for application to field-effect transistor.

Semiconducting thin films consisting of regioregular poly(3-hexylthiophene) (RR-PHT) and poly(N-dodecylacrylamide) (pDDA) were constructed by the Langmuir-Blodgett (LB) technique. A mixture of RR-PHT and pDDA spread from a chloroform solution on a water surface forms a stable monolayer, which can be transferred onto solid substrates by the LB method, yielding a well-defined polymer LB film. Surface morphology studies of the LB film indicate that the RR-PHT is dispersed uniformly throughout the surface.