Publications by authors named "T Mettang"

Article Synopsis
  • - The study tested the long-term effectiveness and safety of a topical emollient (V0034CR) for treating uremic xerosis and chronic kidney disease-related itching, comparing it to a vehicle control in a phase 3 trial.
  • - Over 28 days, patients applying V0034CR showed a significant improvement in xerosis severity and a greater reduction in scaling compared to those using the control, with 60.2% of the V0034CR group responding positively.
  • - While xerosis symptoms returned without treatment after a break, V0034CR helped maintain remission over a longer period, with high patient satisfaction and minimal side effects like minor irritation.
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Background: Chronic pruritus is a clinically heterogeneous symptom that manifests itself with varying duration, intensity, or quality. To date, there is no validated German-language instrument that systematically assesses the relevant parameters. With the support of the Pruritus Research Working Group (Arbeitsgemeinschaft Pruritusforschung, AGP), a questionnaire for the assessment of chronic pruritus (AGP questionnaire) was developed in 2008.

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Background: Hemodialysis (HD) and peritoneal dialysis (PD) are deemed medically equivalent for therapy of end-stage renal disease (ESRD) and reimbursed by the German statutory health insurance (SHI). However, although the home dialysis modality PD is associated with higher patient autonomy than HD, for unknown reasons, PD uptake is low in Germany. Hence, we compared HD with PD regarding health economic outcomes, particularly costs, as potentially relevant factors for the predominance of HD.

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Pruritus is a cross-disciplinary leading symptom of numerous diseases and represents an interdisciplinary diagnostic and therapeutic challenge. In contrast to acute pruritus, chronic pruritus (CP) is a symptom of various diseases that is usually difficult to treat. Scratching and the development of scratch-associated skin lesions can alter the original skin status.

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