A microstructure-based model for a full lamellar-interlamellar displacement and shear strain mapping inside human intervertebral disc core.

The determinant role of the annulus fibrosus interlamellar zones in the intervertebral disc transversal and volumetric responses and hence on their corresponding three-dimensional conducts have been only revealed and appreciated recently. Their consideration in disc modeling strategies has been proven to be essential for the reproduction of correct local strain and displacement fields inside the disc especially in the unconstrained directions of the disc. In addition, these zones are known to be the starting areas of annulus fibrosus circumferential tears and disc delamination failure mode, which is often judged as one of the most dangerous disc failure modes that could evolve with time leading to disc hernia.

A microstructure-based modeling approach to assess aging-sensitive mechanics of human intervertebral disc.

Background And Objective: The human body soft tissues are hierarchic structures interacting in a complex manner with the surrounding biochemical environment. The loss of soft tissues functionality with age leads to more vulnerability regarding to the external mechanical loadings and increases the risk of injuries. As a main example of the human body soft tissues, the intervertebral disc mechanical response evolution with age is explored.

Interlamellar matrix governs human annulus fibrosus multiaxial behavior.

Establishing accurate structure-property relationships for intervertebral disc annulus fibrosus tissue is a fundamental task for a reliable computer simulation of the human spine but needs excessive theoretical-numerical-experimental works. The difficulty emanates from multiaxiality and anisotropy of the tissue response along with regional dependency of a complex hierarchic structure interacting with the surrounding environment. We present a new and simple hybrid microstructure-based experimental/modeling strategy allowing adaptation of animal disc model to human one.

Interlamellar-induced time-dependent response of intervertebral disc annulus: A microstructure-based chemo-viscoelastic model.

The annulus fibrosus of the intervertebral disc exhibits an unusual transversal behavior for which a constitutive representation that considers as well regional effect, chemical sensitivity and time-dependency has not yet been developed, and it is hence the aim of the present contribution. A physically-based model is proposed by introducing a free energy function that takes into account the actual disc annulus structure in relation with the surrounding biochemical environment. The response is assumed to be dominated by the viscoelastic contribution of the extracellular matrix, the elastic contribution of the oriented collagen fibers and the osmo-induced volumetric contribution of the internal fluid content variation.

A two-phase hyperelastic-viscoplastic constitutive model for semi-crystalline polymers: application to polyethylene materials with a variable range of crystal fractions.

Polyethylene-based polymers as biomedical materials can contribute to a wide range of biomechanical applications. Therefore, it is important to identify, analyse, and predict with precision their mechanical behaviour. Polyethylene materials are semi-crystalline systems consisting of both amorphous and crystalline phases interacting in a rather complex manner.