Publications by authors named "T Merono"
Background: Older subjects are at risk of elevated intestinal permeability (IP) which can lead to immune system activation and low-grade systemic inflammation. Dietary changes are a potential strategy to reduce IP. The MaPLE project evaluated the hypothesis that increasing (poly)phenol intake would beneficially impact on several important markers and pathways related to IP.
View Article and Find Full Text PDFBiomarkers associated with dietary fibre intake, as complements to traditional dietary assessment tools, may improve the understanding of its role in human health. Our aim was to discover metabolite biomarkers related to dietary fibre intake and investigate their association with cardiometabolic risk factors. We used data and samples from the Danish Diet Cancer and Health Next Generation (DCH-NG) MAX-study, a one-year observational study with evaluations at baseline, six and 12 months ( = 624, 55% female, mean age: 43 years, 1353 observations).
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- A study on plant-based diets in a Danish population examined how these diets relate to metabolic syndrome (MetS) and identified specific metabolites linked to dietary patterns.
- The research involved 676 participants who provided dietary information and underwent health examinations, leading to the classification of diet quality using healthful (hPDI) and unhealthful (uPDI) indices.
- Findings showed that higher hPDI scores correlated with a decreased risk of MetS, while higher uPDI scores increased the risk, with specific metabolites identified as key indicators of these associations.
Background: Hypothyroidism is associated with impaired glomerular filtration rate (GFR), a recognized cardiovascular disease (CVD), and mortality risk factor. In older adults, this association remains unexplored. We aimed to determine the relationship of elevated TSH with GFR in an elderly population at high CVD risk.
View Article and Find Full Text PDFBerries are rich in (poly)phenols, and these compounds may be beneficial to human health. Estimating berry consumption through self-reported questionnaires has been challenging due to compliance issues and a lack of precision. Estimation via food-derived biomarkers in biofluids was proposed as a complementary alternative.
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