Publications by authors named "T Menter"
Several molecular mismatch assessment approaches exist, but data on their combined use are limited. In this study, we aimed to define distinct risk groups for rejection based on the combination of three molecular mismatch assessment approaches (i.e.
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- * Investigating placental pathology is vital for diagnosing health issues in both the mother and fetus, understanding potential risks for future pregnancies, and determining causes of complications like growth restrictions.
- * Improved terminology and classification of placental conditions aim to enhance collaboration among healthcare professionals in diagnosing and treating related obstetric and fetal disorders.
Background: Recent evidence highlights the pivotal role of natural killer (NK) cells in allograft rejection.
Methods: We explored associations of missing self and gene polymorphisms determining the phenotype and/or functionality of NK cells with microvascular inflammation (MVI) in a single-center cohort of 507 consecutive kidney transplant recipients. Patients were genotyped for killer cell Ig-like receptors and polymorphisms in 4 selected genes (FCGR3AV/F158 [rs396991], KLRC2wt/del, KLRK1HNK/LNK [rs1049174], and rs9916629-C/T).
Article Synopsis
- Research on primary membranoproliferative glomerulonephritis (MPGN) has evolved, leading to the identification of two main types: primary immune complex-MPGN and C3 glomerulopathy, both linked to complement dysregulation.
- A 47-year-old man with primary immune complex-MPGN showed significant improvement after treatment with iptacopan, an oral complement factor B inhibitor, following unsuccessful traditional therapies.
- This case highlights the potential of iptacopan as a promising new treatment option for primary immune complex-MPGN, marking the first documented success in this context.