Publications by authors named "T Mengiste"

Article Synopsis
  • Sorghum anthracnose is a severe disease impacting sorghum yields, with resistant varieties being key for effective management.
  • A study evaluated 25 isolates from Ethiopia, revealing significant differences in virulence among them, with certain isolates showing a high degree of pathogenicity.
  • Findings identified specific sorghum genotypes with resistance potential, highlighting the importance of genetic diversity in developing resilient cultivars.
View Article and Find Full Text PDF
Article Synopsis
  • Sorghum anthracnose, caused by the fungus Colletotrichum sublineola, significantly affects global sorghum productivity, making the identification and introgression of resistant genotypes imperative for improvement.
  • Field experiments on 358 sorghum accessions in Ethiopia uncovered 53 resistant accessions and 213 with varying resistance to local pathogens, leading to a genome-wide association study (GWAS) identifying 38 genetic loci linked to anthracnose resistance.
  • Notably, specific SNPs associated with genes related to immune responses were identified, suggesting targeted genes for further breeding efforts to enhance resistance in sorghum cultivars.
View Article and Find Full Text PDF
Article Synopsis
  • The genetic resources of sorghum in Africa, particularly in Ethiopia, are underutilized for developing new cultivars, despite their potential for local adaptation and improved traits.
  • A study characterized 560 sorghum accessions, using genotyping by sequencing to identify significant genetic diversity, revealing 10 distinct clusters that align with botanical races and ecological types.
  • The findings suggest a strong foundation for hybrid breeding programs by leveraging local germplasm, aiming to enhance productivity and resilience in sorghum cultivars.
View Article and Find Full Text PDF

The receptor-like kinase (RLK) family of receptors and the associated receptor-like cytoplasmic kinases (RLCKs) have expanded in plants because of selective pressure from environmental stress and evolving pathogens. RLCKs link pathogen perception to activation of coping mechanisms. RLK-RLCK modules regulate hormone synthesis and responses, reactive oxygen species (ROS) production, Ca signaling, activation of mitogen-activated protein kinase (MAPK), and immune gene expression, all of which contribute to immunity.

View Article and Find Full Text PDF

Cancer prevention challenges in Ethiopia include limited community awareness and low uptake of screening, which are in part driven by a lack of culturally and linguistically relevant cancer education appropriate for the diverse indigenous communities of this never-colonized nation. In 2022, a comprehensive multi-media breast cancer (BC) awareness campaign was implemented, featuring local cancer experts and survivors, with community-based screening events in the towns of Adama and Mojo. The RE-AIM framework was used to evaluate and describe its reach, effectiveness, adoption, implementation, and maintenance.

View Article and Find Full Text PDF