Publications by authors named "T Meijers"
Background: Transfemoral access is often used when large-bore guide catheters are required for percutaneous coronary intervention (PCI) of complex coronary lesions, especially when large-bore transradial access is contraindicated. Whether the risk of access site complications for these procedures may be reduced by ultrasound-guided puncture is unclear.
Aims: We aimed to show the superiority of ultrasound-guided femoral puncture compared to fluoroscopy-guided access in large-bore complex PCI with regard to access site-related Bleeding Academic Research Consortium 2, 3 or 5 bleeding and/or vascular complications requiring intervention during hospitalisation.
Article Synopsis
- Outcomes for chronic total occlusion percutaneous coronary intervention (PCI) have significantly improved over the past ten years, with a focus on enhancing safety during procedures.
- Vascular access site bleeding is a common complication that can occur during these procedures.
- The review discusses various strategies that have been developed to minimize vascular access site complications in chronic total occlusion PCI.
Article Synopsis
- Recent studies suggest that while transradial access (TRA) is preferred for complex coronary procedures, many patients still require femoral access, especially for chronic total occlusions (CTO), and using ultrasound for puncture may reduce complications.
- A study involving 542 patients is designed to compare ultrasound-guided puncture and fluoroscopy-guided puncture for accessing the femoral artery during complex PCI, focusing on access site complications and major adverse cardiovascular events.
- Ethical approval has been obtained from multiple committees, and the outcomes of the trial will be shared in peer-reviewed journals, with details available on ClinicalTrials.gov under identifier NCT03846752.
Article Synopsis
- This study aimed to compare two types of mechanical circulatory support (MCS) systems, Impella CP and VA-ECMO, in patients undergoing complex high-risk PCI procedures.
- Researchers analyzed data from 41 patients who could not undergo surgery, with no significant differences found in hemodynamic stability or major adverse cardiac events between the two groups.
- The findings suggest that the choice between Impella CP and VA-ECMO does not significantly impact patient outcomes, including mortality rates.
Article Synopsis
- Researchers studied two access methods for heart procedures—transradial access (TRA) and transfemoral access (TFA)—to see which one leads to lower mortality and bleeding in coronary artery disease patients.
- A meta-analysis of data from 21,600 patients across 7 clinical trials found that TRA significantly reduced all-cause mortality (1.6% vs. 2.1%) and major bleeding (1.5% vs. 2.7%) compared to TFA.
- The benefits of TRA were especially notable in patients with moderate or severe anemia, with TRA linked to a 24% reduction in death risk and a 51% reduction in bleeding