Publications by authors named "T Mardesic"
Article Synopsis
- Chronic endometritis is a significant, often undiagnosed cause of infertility, especially affecting in vitro fertilization (IVF) outcomes due to intrauterine inflammation.
- The condition is associated with changes in the endometrial microbiome and characterized by mild or absent symptoms, making diagnosis challenging, typically requiring hysteroscopy and histopathological examinations.
- Empirical antibiotic therapy has been found to increase pregnancy and live birth rates in women with confirmed chronic endometritis, highlighting the need for improved diagnostic criteria and awareness of the condition's reproductive implications.*
Study Question: Is it possible to define a set of performance indicators (PIs) for clinical work in ART, which can create competency profiles for clinicians and for specific clinical process steps?
Summary Answer: The current paper recommends six PIs to be used for monitoring clinical work in ovarian stimulation for ART, embryo transfer, and pregnancy achievement: cycle cancellation rate (before oocyte pick-up (OPU)) (%CCR), rate of cycles with moderate/severe ovarian hyperstimulation syndrome (OHSS) (%mosOHSS), the proportion of mature (MII) oocytes at ICSI (%MII), complication rate after OPU (%CoOPU), clinical pregnancy rate (%CPR), and multiple pregnancy rate (%MPR).
What Is Known Already: PIs are objective measures for evaluating critical healthcare domains. In 2017, ART laboratory key PIs (KPIs) were defined.
Introduction: During the 30th symposium of assisted reproduction held on November 11, 2020 in Brno, the solved problems in reproductive medicine in the Czech Republic in 2020 were presented. The selected topics have concerned not only current issues in the field of clinical embryology and genetics as well as gynecology, but also legislation and ethics. Discussed topics: 1.
View Article and Find Full Text PDFObjectives: To compare results after stimulation with corifollitropin alfa (Elonva) in unselected group of women entering for the first time in in vitro fertilization programme (IVF) with results from Phase III randomized trials with selected groups of women.
Design: Prospective study.
Setting: Sanatorium Pronatal, Praha.
Objective: To demonstrate successful restoration of ovarian function after ovarian transplantation in young woman with premature ovarian failure after gonadotoxic treatment of breast carcinoma and to discuss its possibilities.
Design: Case report.
Setting: Sanatorium Pronatal, Prague.