Publications by authors named "T M Siegmund"
Understanding bone strength is important when assessing bone diseases and their treatment. Bending experiments are often used to determine strength. Then, flexural stresses are calculated from elastic bending theory.
View Article and Find Full Text PDFQuasi-brittle fracture mechanics is used to evaluate fracture of human cortical bone in aging. The approach is demonstrated using cortical bone bars extracted from one 92-year-old human male cadaver. In-situ fracture mechanics experiments in a 3D X-ray microscope are conducted.
View Article and Find Full Text PDFToday, continuous glucose monitoring (CGM) is a standard diagnostic option for patients with diabetes, at least for those with type 1 diabetes and those with type 2 diabetes on insulin therapy, according to international guidelines. The switch from spot capillary blood glucose measurement to CGM was driven by the extensive and immediate support and facilitation of diabetes management CGM offers. In patients not using insulin, the benefits of CGM are not so well studied/obvious.
View Article and Find Full Text PDFArticle Synopsis
- A 2D XFEM model was created to analyze how three-point bending tests on human bone are affected by hydration levels, revealing that dehydration reduces critical damage strains by approximately 50%.
- The study found that variations in critical damage strains, particularly at the cement lines, significantly influence crack paths and fracture toughness, especially when the bone is hydrated.
- These findings offer new insights into the micromechanisms of bone fracture related to dehydration, suggesting potential applications for understanding aging, disease, and medical treatments in the context of bone health.